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  1. Few chronic kidney disease (CKD) risk prediction models have been investigated in low- and middle-income areas worldwide. We developed new risk scores for predicting incident CKD in low- and middle-income rura...

    Authors: Jiangping Wen, Jie Hao, Ye Zhang, Kai Cao, Xiaohong Zhang, Jiang Li, Xinxin Lu and Ningli Wang
    Citation: BMC Nephrology 2020 21:120
    Content type: Research article Published on:

  2. Little is known about the relationship between acute kidney injury (AKI) and outcomes after acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We aimed to investigate associations between AK...

    Authors: Atsushi Hirayama, Tadahiro Goto and Kohei Hasegawa
    Citation: BMC Nephrology 2020 21:116
    Content type: Research article Published on:

  3. This study was conducted to evaluate and update the current prevalence of and risk factors for chronic kidney disease (CKD) and diabetic kidney disease (DKD) in a central Chinese urban population.

    Authors: Jia-Yu Duan, Guang-Cai Duan, Chong-Jian Wang, Dong-Wei Liu, Ying-Jin Qiao, Shao-Kang Pan, Deng-Ke Jiang, Yong Liu, Zi-Hao Zhao, Lu-Lu Liang, Fei Tian and Zhang-Suo Liu
    Citation: BMC Nephrology 2020 21:115
    Content type: Research article Published on:

  4. Non-adherence (NA) to immunosuppressants (IS) among renal transplant recipients (RTRs) is associated with higher risk of allograft rejection, graft loss, and mortality. A precise measurement of NA is indispens...

    Authors: Marietta Lieb, Tobias Hepp, Mario Schiffer, Mirian Opgenoorth and Yesim Erim
    Citation: BMC Nephrology 2020 21:114
    Content type: Research article Published on:

  5. The advent of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with advanced malignancies. On the other hand, these drugs might cause immune-related adverse events (irAE...

    Authors: Natsumi Matsuoka, Kenji Tsuji, Eiki Ichihara, Takayuki Hara, Kazuhiko Fukushima, Kishio Toma, Shinji Kitamura, Kenichi Inagaki, Hitoshi Sugiyama and Jun Wada
    Citation: BMC Nephrology 2020 21:113
    Content type: Case report Published on:

  6. The purse-string suture has been widely used for bleeding control after percutaneous interventions through arteriovenous fistula (AVF) and graft (AVG), and it requires suture removal the next day. This study a...

    Authors: Qiquan Lai, Hui Zhang, Bo Chen, Xuejing Gao, Ling Chen, Bo Tu, Baifei Li, Bo Hu, Fan He, Yong Xu and Ziming Wan
    Citation: BMC Nephrology 2020 21:112
    Content type: Research article Published on:

  7. Monoclonal serum free light chains (sFLC) are a well-known cause of renal impairment (RI) in patients with multiple myeloma (MM). As an indicator of monoclonality, sFLC ratio has acquired a key role in the dia...

    Authors: Alícia Molina-Andújar, Pau Robles, Maria T. Cibeira, Enrique Montagud-Marrahi, Elena Guillen, Marc Xipell, Miquel Blasco, Esteban Poch, Laura Rosiñol, Joan Bladé and Luis F. Quintana
    Citation: BMC Nephrology 2020 21:111
    Content type: Research article Published on:

  8. Encapsulating-peritoneal-sclerosis (EPS) is a rare, but serious and life-threatening complication of peritoneal dialysis (PD). Treatment of EPS consists of discontinuation of PD and maintenance of nutritional ...

    Authors: Vassilios Liakopoulos, Panagiotis I. Georgianos, Vasilios Vaios, Stefanos Roumeliotis, Apostolos Karligkiotis and Pantelis E. Zebekakis
    Citation: BMC Nephrology 2020 21:110
    Content type: Case report Published on:

  9. Human leukocyte antigen (HLA)-G is a non-classical HLA molecule with immunomodulant and immunosuppressive functions, involved in transplantation tolerance. HLA-G14bp ins/del polymorphism in exon 8 has been ass...

    Authors: Daniela Piancatelli, Daniela Maccarone, Alessia Colanardi, Pierluigi Sebastiani, Katia Clemente, Samuele Iesari, Quirino Lai and Francesco Pisani
    Citation: BMC Nephrology 2020 21:109
    Content type: Research article Published on:

  10. Prior papers have been inconsistent regarding how much creatinine clearance (CrCl) overestimates glomerular filtration rate (GFR). A recent cross-sectional study suggested that measurement error alone could en...

    Authors: Xuehan Zhang, Andrew D. Rule, Charles E. McCulloch, John C. Lieske, Elaine Ku and Chi-yuan Hsu
    Citation: BMC Nephrology 2020 21:108
    Content type: Research article Published on:

  11. The conjunction of hepatitis and renal disease can be seen in several clinical context, including karyomegalic nephritis (KIN). Karyomegalic nephritis (KIN) is a rare genetic disease, with less than 50 cases r...

    Authors: Jonathan Dash, Patrick Saudan, Ariane Paoloni-Giacobino, Solange Moll and Sophie de Seigneux
    Citation: BMC Nephrology 2020 21:107
    Content type: Case report Published on:

  13. Following publication of the original article [1], we have been notified that the approved number by the Ethical Committee was given incorrectly. In the section “Methods” stated that: The Central Ethical Commi...

    Authors: Rita Jacobs, Patrick M. Honore, Marc Diltoer and Herbert D. Spapen
    Citation: BMC Nephrology 2020 21:105
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2016 17:119

  14. Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by systemic thrombotic microangiopathy (TMA) reflected by hemolysis, anemia, thrombocytopenia and systemic organ injury. The optimal ma...

    Authors: Christoph Nunius, Maike Büttner-Herold, Simone Bertz, Mario Schiffer and Bjoern Buchholz
    Citation: BMC Nephrology 2020 21:104
    Content type: Case report Published on:

  15. High water hardness associated with high water fluoride and the geographical distribution of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka are well correlated. We undertook this study to obser...

    Authors: Thanusha Perera, Shirani Ranasinghe, Neil Alles and Roshitha Waduge
    Citation: BMC Nephrology 2020 21:103
    Content type: Research article Published on:

  16. P. multocida (Pasteurella multocida) is animal-sourced gram-negative coccobacillus which can be transmitted to human through many animals including household pets. P. multocida induced peritoneal dialysis-related...

    Authors: Haoran Mu, Man Yang, Yueyue Zhang, Yajing Zhang, Juan Wang, Weijie Yuan and Shu Rong
    Citation: BMC Nephrology 2020 21:102
    Content type: Case report Published on:

  17. Little is known about the changes in disease makers and risk factors in patients with chronic kidney disease (CKD) under nephrological care in Africa. This study aimed to evaluate the baseline level of markers...

    Authors: Halle Marie Patrice, Kengne Andre Pascal, Kaze Folefack François, Djantio Hilaire, Doualla Marie Solange, Ashuntantang Enow Gloria and Choukem Siméon Pierre
    Citation: BMC Nephrology 2020 21:101
    Content type: Research article Published on:

  18. A randomized trial of a pedometer-based intervention with weekly activity goals led to a modest increase in step count among dialysis patients. In a secondary analysis, we investigated the effect of this inter...

    Authors: Anoop Sheshadri, Piyawan Kittiskulnam, Jennifer C. Lai and Kirsten L. Johansen
    Citation: BMC Nephrology 2020 21:100
    Content type: Research article Published on:

  19. Stage 5 chronic kidney disease (CKD-5) patients on haemodialysis (HD) are at high risk of accidental falls. Previous research has shown that frailty is one of the primary contributors to the increased risk of ...

    Authors: Tobia Zanotto, Thomas H. Mercer, Marietta L. van der Linden, Robert Rush, Jamie P. Traynor, Colin J. Petrie, Arthur Doyle, Karen Chalmers, Nicola Allan, Ilona Shilliday and Pelagia Koufaki
    Citation: BMC Nephrology 2020 21:99
    Content type: Research article Published on:

  20. Acute kidney injury (AKI) is highly associated with mortality risk in children worldwide. Trauma can lead to AKI and is a leading cause of pediatric death in Africa. However, there is no information regarding ...

    Authors: Erica C. Bjornstad, William Muronya, Zachary H. Smith, Keisha Gibson, Amy K. Mottl, Anthony Charles, Stephen W. Marshall, Yvonne M. Golightly, Charles K. Munthali and Emily W. Gower
    Citation: BMC Nephrology 2020 21:98
    Content type: Research article Published on:

  21. Growing evidence has shown that the gut-renal connection and gut microbiota dysbiosis play a critical role in immunoglobulin A nephropathy (IgAN). However, the fecal microbiome profile in Chinese patients with...

    Authors: Xiaofang Hu, Jie Du, Yuhong Xie, Qiong Huang, Yi Xiao, Juan Chen, Siyuan Yan, Zhicheng Gong and Shaxi Ouyang
    Citation: BMC Nephrology 2020 21:97
    Content type: Research article Published on:

  22. Thrombotic microangiopathy (TMA) syndromes are characterized by the association of hemolytic anemia, thrombocytopenia and organ injury due to arteriolar and capillary thrombosis.

    Authors: C. Philipponnet, J. Desenclos, M. Brailova, J. Aniort, J. L. Kemeny, C. Deville, V. Fremeaux-Bacchi, B. Souweine and A. E. Heng
    Citation: BMC Nephrology 2020 21:96
    Content type: Case report Published on:

  23. Chronic kidney disease (CKD) is growing population health concern worldwide, and with early identification and effective management, kidney disease progression can be slowed or prevented. Most patients with ri...

    Authors: Elizabeth P. Neale, Justin Middleton and Kelly Lambert
    Citation: BMC Nephrology 2020 21:83
    Content type: Research article Published on:

  24. Acute kidney injury (AKI) is a common complication among human immunodeficiency virus (HIV)-infected patients resulting in increased morbidity and mortality. Continuous renal replacement therapy (CRRT) is a us...

    Authors: Hebing Guo, Jingyuan Liu, Lin Pu, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong and Ang Li
    Citation: BMC Nephrology 2020 21:95
    Content type: Research article Published on:

  25. In low-middle-income countries (LMICs), data regarding acute kidney injury (AKI) are scarce. AKI patients experience delayed diagnosis. This study aimed to evaluate whether delayed nephrologist consultation (N...

    Authors: Ginivaldo Victor Ribeiro do Nascimento, Marcela do Nascimento Silva, Juarez Duarte de Carvalho Neto, Ludgero Ribeiro Feitosa Filho and Jessica Duarte Antão
    Citation: BMC Nephrology 2020 21:94
    Content type: Research article Published on:

  26. Pneumocystis pneumonia (PCP) is a life-threatening fungal infection that can occur in kidney transplantation (KT) recipients. A growing number of KT recipients are receiving perioperative treatment with rituxi...

    Authors: Young Hoon Kim, Jee Yeon Kim, Dong Hyun Kim, Youngmin Ko, Ji Yoon Choi, Sung Shin, Joo Hee Jung, Su-Kil Park, Sung-Han Kim, Hyunwook Kwon and Duck Jong Han
    Citation: BMC Nephrology 2020 21:93
    Content type: Research article Published on:

  27. The efficacy and safety of minimisation of immunosuppression including early steroid withdrawal in kidney transplant recipients treated with Basiliximab induction remains unclear.

    Authors: Mysore K. Phanish, Richard P. Hull, Peter A. Andrews, Joyce Popoola, Edward J. Kingdon and Iain A. M. MacPhee
    Citation: BMC Nephrology 2020 21:92
    Content type: Research article Published on:

  28. Nutritional factors are associated with high mortality and morbidity in dialysis patients, and protein-energy wasting is regarded as an important one. The modality of dialysis may affect patients’ dietary beha...

    Authors: Seon-Mi Kim, Byung Chin Kang, Hyun-Jung Kim, Min-Sook Kyung, Hyung Jung Oh, Jung-Hyun Kim, Oran Kwon and Dong-Ryeol Ryu
    Citation: BMC Nephrology 2020 21:91
    Content type: Research article Published on:

  29. DD was found to be associated with acute myocardial infarction (AMI) and renal insufficiency. However, it is uncertain whether DD is an independent risk factor of CI-AKI in patients undergoing pPCI.

    Authors: Kai-Yang Lin, Han-Chuan Chen, Hui Jiang, Sun-Ying Wang, Hong-Mei Chen, Zhi-Yong Wu, Feng Jiang, Yan-Song Guo and Peng-Li Zhu
    Citation: BMC Nephrology 2020 21:90
    Content type: Research article Published on:

  30. Left ventricular (LV) myocardial longitudinal diastolic strain rate measured by two-dimensional speckle tracking imaging (2D-STI) was proved to have a better correlation with the LV diastolic function. We aime...

    Authors: Jing Zhu, Fei Shi, Tao You, Chao Tang and Jianchang Chen
    Citation: BMC Nephrology 2020 21:89
    Content type: Research article Published on:

  31. Reductions in health-related quality of life (HRQoL) in patients with chronic kidney disease (CKD) are thought to be exacerbated by the low hemoglobin (Hb) levels that define anemia, a common complication of C...

    Authors: Heleen van Haalen, James Jackson, Bruce Spinowitz, Gary Milligan and Rebecca Moon
    Citation: BMC Nephrology 2020 21:88
    Content type: Research article Published on:

  32. Interstitial fibrosis (IF) on kidney biopsy is one of the most potent risk factors for kidney disease progression. The furosemide stress test (FST) is a validated tool that predicts the severity of acute kidne...

    Authors: Jesús Rivero, Francisco Rodríguez, Virgilia Soto, Etienne Macedo, Lakhmir S. Chawla, Ravindra L. Mehta, Sucheta Vaingankar, Pranav S. Garimella, Carlos Garza and Magdalena Madero
    Citation: BMC Nephrology 2020 21:87
    Content type: Research article Published on:

  33. Vascular calcification (VC) is a risk factor for cardiovascular disease in end-stage renal disease (ESRD) patients undergoing maintenance haemodialysis (MHD). However, evidence is still insufficient about the ...

    Authors: Sung Keun Park, Won Joong Kim, Hyun Jin Kim, Hae Won Kim, Beom Kim, Hong Joo Lee, So-Young Lee, Yu Ho Lee, Dong-Jin Kim, Kyung-Hwan Jeong, Ju-Young Moon, Sang-Ho Lee, Shin Young Ahn, Gang Jee Ko, Jae-Hong Ryoo and Dong-Young Lee
    Citation: BMC Nephrology 2020 21:86
    Content type: Research article Published on:

  34. Chronic kidney disease (CKD) has been identified as a significant direct marker for cognitive decline, but controversy exists regarding the magnitude of the association of kidney function with cognitive declin...

    Authors: Laurien E. Zijlstra, Stella Trompet, Simon P. Mooijaart, Marjolijn van Buren, Naveed Sattar, David J. Stott and J. Wouter Jukema
    Citation: BMC Nephrology 2020 21:81
    Content type: Research article Published on:

  36. Renalase is a flavoprotein that plays a protective role in chronic kidney disease (CKD) and cardiovascular diseases. The secretion and way of action of this protein are still discussed. The aim of our study wa...

    Authors: Natalia M. Serwin, Magda Wiśniewska, Elżbieta Cecerska-Heryć, Krzysztof Safranow, Edyta Skwirczyńska and Barbara Dołęgowska
    Citation: BMC Nephrology 2020 21:77
    Content type: Research article Published on:

  37. Initial presentation of peritoneal dialysis associated infectious peritonitis can be clinically indistinguishable from Clostridioides difficile infection (CDI) and both may demonstrate a cloudy dialysate. Empiric...

    Authors: Kairav J. Shah, Kartikeya Cherabuddi, Kalynn B. Pressly, Kaitlyn L. Wright and Ashutosh Shukla
    Citation: BMC Nephrology 2020 21:76
    Content type: Case report Published on:

  38. Low birth weight (LBW) is associated with end-stage kidney disease and hypertension and is considered to be a surrogate marker of low nephron number. Low nephron number is hypothesized to contribute to glomeru...

    Authors: Yuriko Shiozaki, Tomoyuki Fujikura, Shinsuke Isobe, Ibuki Takatsuka, Taichi Sato, Daiki Goto, Sayaka Ishigaki, Naro Ohashi and Hideo Yasuda
    Citation: BMC Nephrology 2020 21:75
    Content type: Case report Published on:

  39. Karyomegalic interstitial nephritis (KIN) is a rare hereditary cause of chronic kidney disease. It typically causes progressive renal impairment with haemoproteinuria requiring renal replacement therapy before...

    Authors: Steven Law, Julian Gillmore, Janet A. Gilbertson, Paul Bass and Alan D. Salama
    Citation: BMC Nephrology 2020 21:74
    Content type: Case report Published on:

  40. Chronic Kidney Disease (CKD) in patients with type 2 diabetes enhances the cardiovascular risk profiles and disease, and is a strong predictor of progression to end-stage kidney disease. Early diagnosis is enc...

    Authors: Frederick C. F. Otieno, Elijah N. Ogola, M. W. Kimando and Kenn Mutai
    Citation: BMC Nephrology 2020 21:73
    Content type: Research article Published on:

  41. Chronic kidney disease (CKD) is increasing worldwide, and the majority of the CKD burden is in low- and middle-income countries (LMICs). However, there is wide variability in global access to kidney care thera...

    Authors: David Flood, Katharine Wilcox, Andrea Aguilar Ferro, Carlos Mendoza Montano, Joaquin Barnoya, Pablo Garcia, Randall Lou-Meda, Peter Rohloff and Anita Chary
    Citation: BMC Nephrology 2020 21:71
    Content type: Research article Published on:

  42. A positive pregnancy test in acute or chronically ill patients has implications for the use of potentially mutagenic or teratogenic products in urgent medical therapies such as the use of chemotherapies or the...

    Authors: Natalja Haninger-Vacariu, Harald Herkner, Matthias Lorenz, Marcus Säemann, Andreas Vychytil, Martin Jansen, Rodrig Marculescu, Reinhard Kramar, Gere Sunder-Plassmann and Alice Schmidt
    Citation: BMC Nephrology 2020 21:70
    Content type: Research article Published on:

  44. IgA deficiency associated with glomerulonephritis is rare. In particular, there is no prior report regarding the association between IgA deficiency and membranoproliferative glomerulonephritis (MPGN) in childr...

    Authors: Keisuke Sugimoto, Takuji Enya, Kohei Miyazaki, Tomoki Miyazawa, Tsukasa Takemura and Mitsuru Okada
    Citation: BMC Nephrology 2020 21:68
    Content type: Case report Published on:

  45. Hemodialysis sessions frequently become unstable from complications such as intradialytic hypotension and untoward symptoms. Previous patient safety initiatives promote prevention of treatment complications; y...

    Authors: Pei-Yi Kuo, Rajiv Saran, Marissa Argentina, Michael Heung, Jennifer Bragg-Gresham, Sarah Krein, Brenda W. Gillespie, Kai Zheng and Tiffany C. Veinot
    Citation: BMC Nephrology 2020 21:67
    Content type: Research article Published on:

  46. Information about renal diseases in children is available from national registries of renal biopsies. Aim of the study was to compare the clinical presentation of glomerular diseases and tubulointerstitial spa...

    Authors: Adela Arapović, Katarina Vukojević, Natalija Filipović, Merica Glavina Durdov, Danica Ljubanović-Galešić, Mirna Saraga-Babić, Sandra Prgomet, Ana Simičić Majce, Anja Belavić, Dijana Borić Škaro, Dragan Ljutić and Marijan Saraga
    Citation: BMC Nephrology 2020 21:65
    Content type: Research article Published on:

  47. Calcific Uremic Arteriolopathy (CUA) is a rare disease, causing painful skin ulcers in patients with end stage renal disease. Recommendations for CUA management and treatment are lacking.

    Authors: Raphaël Gaisne, Morgane Péré, Victorio Menoyo, Maryvonne Hourmant and David Larmet-Burgeot
    Citation: BMC Nephrology 2020 21:63
    Content type: Research article Published on:

  48. Limited evidence has indicated that addition of a steroidal mineralocorticoid receptor antagonist (MRA) to the standard of care reduces proteinuria in patients with diabetic kidney disease (DKD); however, ther...

    Authors: Michael Blankenburg, Csaba P. Kovesdy, Anne-Kathrin Fett, Raymond G. Griner and Alain Gay
    Citation: BMC Nephrology 2020 21:61
    Content type: Research article Published on:

  49. The application of laparoscopic catheterization technology in peritoneal dialysis (PD) patients has recently increased. However, the advantages and disadvantages of laparoscopic versus conventional open PD cat...

    Authors: Mei-Lan Sun, Yong Zhang, Bo Wang, Te-An Ma, Hong Jiang, Shou-Liang Hu, Piao Zhang and Yan-Hong Tuo
    Citation: BMC Nephrology 2020 21:60
    Content type: Research article Published on:

  50. Sickle cell disease (SCD) is a highly prevalent genetic disease worldwide. In the natural evolution of SCD, glomerular lesions can develop, presenting histopathological patterns of segmental or focal membranop...

    Authors: Precil Diego Miranda de Menezes Neves, Bernardo Vergara Reichert, Ramaiane Aparecida Bridi, Luis Yu, Cristiane Bitencourt Dias, Rafaela Brito Bezerra Pinheiro, Leonardo de Abreu Testagrossa, Lívia Barreira Cavalcante, Denise Maria Avancini Costa Malheiros, Lectícia Barbosa Jorge and Viktoria Woronik
    Citation: BMC Nephrology 2020 21:56
    Content type: Case report Published on:
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BMC Nephrology

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