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  1. Patients with nephrotic syndrome are at an increased risk of thromboembolic events (TEs). However, this association has not been thoroughly investigated in adult patients with idiopathic membranous nephropathy...

    Authors: Sanjeev Kumar, Ananda Chapagain, Dorothea Nitsch and Muhammad M Yaqoob
    Citation: BMC Nephrology 2012 13:107
  2. Hemodiafiltration (HDF), as a convective blood purification technique, has been associated with favorable outcomes improved phosphate control, removal of middle-molecules such as Beta2-microglobulin and the oc...

    Authors: Franklin G Mora-Bravo, Guadalupe De-La-Cruz, Sonia Rivera, Alfonso Mariscal Ramírez, Jochen G Raimann and Héctor Pérez-Grovas
    Citation: BMC Nephrology 2012 13:106
  3. Bone marrow (BM) stem cells have been reported to contribute to tissue repair after kidney injury model. However, there is no direct evidence so far that BM cells can trans-differentiate into renal stem cells.

    Authors: Xiaohua Jia, Xiaoqiang Xie, Guowei Feng, He Lű, Qinjun Zhao, Yongzhe Che, Yizhou Zheng, Zhongchao Han, Yong Xu, Zongjin Li and Deling Kong
    Citation: BMC Nephrology 2012 13:105
  4. The relationship between glycemic control and lipid abnormalities with urinary albumin-creatinine ratio (ACR) in chronic kidney disease (CKD) patients with diabetes mellitus (DM) is unknown. We sought to inves...

    Authors: Subhasish Bose, Andrew S Bomback, Nehal N Mehta, Shu-Cheng Chen, Suying Li, Adam Whaley-Connell, Joseph Benjamin and Peter A McCullough
    Citation: BMC Nephrology 2012 13:104
  5. Limited data exist on the impact of living kidney donation on the donor-recipient relationship. Purpose of this study was to explore motivations to donate or accept a (living donor) kidney, whether expected re...

    Authors: Ingrid B de Groot, Karen Schipper, Sandra van Dijk, Paul J M van der Boog, Anne M Stiggelbout, Andrzej G Baranski and Perla J Marang-van de Mheen
    Citation: BMC Nephrology 2012 13:103
  6. The vitamin D receptor activator paricalcitol has been shown to reduce albuminuria. Whether this is a unique property of paricalcitol, or common to all vitamin D analogues, is unknown. The primary aim of this ...

    Authors: Hanne Skou Jørgensen, Simon Winther, Johan Vestergaard Povlsen and Per Ivarsen
    Citation: BMC Nephrology 2012 13:102
  7. This retrospective study was undertaken to determine the incidence of kidney dysfunction (KD) and to identify potential risk factors contributing to development of KD in orthopaedic population following an ele...

    Authors: Konstantinos Kateros, Christos Doulgerakis, Spyridon P Galanakos, Vasileios I Sakellariou, Stamatios A Papadakis and George A Macheras
    Citation: BMC Nephrology 2012 13:101
  8. Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients...

    Authors: Chun-Chuan Lee, Chih-Jen Wu, Li-Hua Chou, Su-Mei Shen, Sheng-Fang Chiang, Pi-Chu Jen, Mei-Ching Yeh and Chi-Feng Pan
    Citation: BMC Nephrology 2012 13:100
  9. Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/repe...

    Authors: Michael Osthoff, Vanja Piezzi, Theresia Klima, Andreas Christ, Ivana Marana, Sabine Hartwiger, Tobias Breidthardt, Giancarlo Marenzi, Marten Trendelenburg and Christian Mueller
    Citation: BMC Nephrology 2012 13:99
  10. Coronary collateral circulation plays an important role to protect myocardium from ischemia, preserve myocardial contractility and reduce cardiovascular events. Chronic kidney disease (CKD) is associated with ...

    Authors: Po-Chao Hsu, Suh-Hang Juo, Ho-Ming Su, Szu-Chia Chen, Wei-chung Tsai, Wen-Ter Lai, Sheng-Hsiung Sheu and Tsung-Hsien Lin
    Citation: BMC Nephrology 2012 13:98
  11. The status of immunocompromised patients is well recognized in end stage renal disease (ESRD). As described recently, this acquired immune dysfunction in the uremic milieu may be one of the main pathogenic fac...

    Authors: Shih-Yi Lin, Jiung-Hsiun Liu, Shu-Ming Wang, I-Kuan Wang, Chen-An Tsai, Yao-lung Liu, Hsin-Hung Lin, Chiz-Chung Chang and Chiu-Ching Huang
    Citation: BMC Nephrology 2012 13:97
  12. Because of the rapid growth in elderly population, polypharmacy has become a serious public health issue worldwide. Although acute renal failure (ARF) is one negative consequence of polypharmacy, the associati...

    Authors: Yi-Ping Chang, San-Kuei Huang, Ping Tao and Ching-Wen Chien
    Citation: BMC Nephrology 2012 13:96
  13. Peginesatide is a peptide-based erythropoiesis-stimulating agent that was designed and engineered to stimulate specifically the erythropoietin receptor dimer that governs erythropoiesis. The primary objective ...

    Authors: Anatole Besarab, Steven N Zeig, Edouard R Martin, Pablo E Pergola, Frederick C Whittier, Raja I Zabaneh, Brigitte Schiller, Martha Mayo, Carol A Francisco, Krishna R Polu and Anne-Marie Duliege
    Citation: BMC Nephrology 2012 13:95
  14. Cardiovascular disease (CVD) is the main cause of death in patients on chronic dialysis. The question whether dialysis modality impacts cardiovascular risk remains to be addressed. China Collaborative Study on...

    Authors: Fanfan Hou, Jianping Jiang, Jianghua Chen, Xueqing Yu, Qiugen Zhou, Pingyan Chen, Changlin Mei, Fei Xiong, Wei Shi, Wei Zhou, Xusheng Liu, Shiren Sun, Di Xie, Jun Liu, Ping Zhang, Xiao Yang…
    Citation: BMC Nephrology 2012 13:94
  15. Renal failure is one of the most serious complications associated with autosomal dominant polycystic kidney disease (ADPKD). To date, early markers have failed to predict renal function deterioration at the ea...

    Authors: Hayne Cho Park, Jin Ho Hwang, Ah-Young Kang, Han Ro, Myung-Gyu Kim, Jung Nam An, Ji In Park, Seung Hyup Kim, Jaeseok Yang, Yun Kyu Oh, Kook-Hwan Oh, Jung Woo Noh, Hae Il Cheong, Young-Hwan Hwang and Curie Ahn
    Citation: BMC Nephrology 2012 13:93
  16. Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin ...

    Authors: Bunyong Phakdeekitcharoen and Kochawan Boonyawat
    Citation: BMC Nephrology 2012 13:92
  17. Polycystic Kidney Disease (PKD) is a genetic condition in which dedifferentiated and highly proliferative epithelial cells form renal cysts and is frequently treated by renal transplantation. Studies have repo...

    Authors: Elizabeth Verghese, Chad Johnson, John F Bertram, Sharon D Ricardo and James A Deane
    Citation: BMC Nephrology 2012 13:91
  18. Chronic kidney disease is an important public health threat. Such patients present high morbidity and mortality due to cardiovascular disease, with low quality of life and survival, and also high expenditure r...

    Authors: Franklin C Barcellos, Iná S Santos, Grégore Iven Mielke, Fabrício B del Vecchio and Pedro C Hallal
    Citation: BMC Nephrology 2012 13:90
  19. The renin-angiotensin-aldosterone system (RAAS) plays an important role in the progression of chronic kidney disease (CKD). Although dual RAAS inhibition results in worse renal outcomes than monotherapy in hig...

    Authors: Szu-yuan Li, Yung-Tai Chen, Wu-Chang Yang, Der-Cherng Tarng, Chih-Ching Lin, Chih-Yu Yang and Wen-Sheng Liu
    Citation: BMC Nephrology 2012 13:89
  20. Although several studies have demonstrated early survival advantages with peritoneal dialysis (PD) over hemodialysis (HD), the reason for the excess mortality observed among incident HD patients remains to be ...

    Authors: Luis Coentrão, Carla Santos-Araújo, Claudia Dias, Ricardo Neto and Manuel Pestana
    Citation: BMC Nephrology 2012 13:88
  21. Kidney disease is associated with an increased total mortality and cardiovascular morbimortality in the general population and in patients with Type 2 diabetes. The aim of this study is to determine the preval...

    Authors: Gabriel Coll-de-Tuero, Manel Mata-Cases, Antonio Rodriguez-Poncelas, Josep MA Pepió, Pilar Roura, Belen Benito, Josep Franch-Nadal and Marc Saez
    Citation: BMC Nephrology 2012 13:87
  22. One hallmark of uremia is the impairment of neuro-cognitive function. Anecdotal clinical description from the early days of chronic dialysis therapy impressively illustrates the improvement of those functions ...

    Authors: Sabrina Schneider, Anne-Kathrin Malecki, Olaf Boenisch, Robby Schönfeld and Jan T Kielstein
    Citation: BMC Nephrology 2012 13:86
  23. Chronic kidney disease is common in HIV positive patients and renal tubular dysfunction has been reported in those receiving combination antiretroviral therapy (cART). Tenofovir (TFV) in particular has been li...

    Authors: Lucy J Campbell, Tracy Dew, Rashim Salota, Emily Cheserem, Lisa Hamzah, Fowzia Ibrahim, Pantelis A Sarafidis, Caje F Moniz, Bruce M Hendry, Mary Poulton, Roy A Sherwood and Frank A Post
    Citation: BMC Nephrology 2012 13:85
  24. IgA nephropathy has been reported as a renal involvement in Crohn’s disease. Crescentic IgA nephropathy, which accounts for fewer than 5% of cases of IgA nephropathy, has a poorer prognosis than other forms of...

    Authors: Ji-Young Choi, Chung Hoon Yu, Hee-Yeon Jung, Min Kyu Jung, Yong-Jin Kim, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim and Sun-Hee Park
    Citation: BMC Nephrology 2012 13:84
  25. Sickle cell disease (SCD) leads to tissue hypoxia resulting in chronic organ dysfunction including SCD associated nephropathy. The goal of our study was to determine the best equation to estimate glomerular fi...

    Authors: Jean-Benoît Arlet, Jean-Antoine Ribeil, Gilles Chatellier, Dominique Eladari, Sophie De Seigneux, Jean-Claude Souberbielle, Gérard Friedlander, Marianne de Montalembert, Jacques Pouchot, Dominique Prié and Marie Courbebaisse
    Citation: BMC Nephrology 2012 13:83
  26. Transparency in quality of care (QoC) is stimulated and hospitals are compared and judged on the basis of indicators of performance on specific treatment targets. In patients with chronic kidney disease, QoC d...

    Authors: Mieke J Peeters, Arjan D van Zuilen, Jan AJG van den Brand, Peter J Blankestijn, Marc AGJ ten Dam and Jack FM Wetzels
    Citation: BMC Nephrology 2012 13:82
  27. Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chron...

    Authors: Sophia Ross, Kerstin Benz, Katja Sauerstein, Kerstin Amann, Jörg Dötsch and Katalin Dittrich
    Citation: BMC Nephrology 2012 13:81
  28. The pathogenesis of pulmonary hypertension (PH) in hemodialysis is still unclear. The aim of this study was to identify the risk factors associated with the presence of PH in chronic hemodialysis patients and ...

    Authors: Hugo Hyung Bok Yoo, Luis Cuadrado Martin, Ana Claudia Kochi, Lidiane Silva Rodrigues-Telini, Pasqual Barretti, Jacqueline Teixeira Caramori, Beatriz Bojikian Matsubara, Silméia Garcia Zannati-Bazan, Roberto Jorge da Silva Franco and Thais Thomaz Queluz
    Citation: BMC Nephrology 2012 13:80
  29. ADPKD affects approximately 1:1000 of the worldwide population. It is caused by mutations in two genes, PKD1 and PKD2. Although allelic variation has some influence on disease severity, genic effects are strong, ...

    Authors: Caroline Robinson, Thomas F Hiemstra, Deborah Spencer, Sarah Waller, Laura Daboo, Fiona E Karet Frankl and Richard N Sandford
    Citation: BMC Nephrology 2012 13:79
  30. This study tests the hypotheses that health-related quality of life (HRQOL) in prevalent dialysis patients with diabetes is lower than in dialysis patients without diabetes, and is at least as poor as diabetic...

    Authors: Tone Britt Hortemo Østhus, Nanna von der Lippe, Lis Ribu, Tone Rustøen, Torbjørn Leivestad, Toril Dammen and Ingrid Os
    Citation: BMC Nephrology 2012 13:78
  31. The worldwide increasing trend of chronic kidney disease (CKD) is of great concern and the role of heart disease deserves longitudinal studies. This study investigated the risk of developing CKD among patients...

    Authors: Jiung-Hsiun Liu, Shih-Yi Lin, Chung-Yi Hsu, Hsin-Hung Lin, Chih-Chia Liang, Fung-Chang Sung and Chiu-Ching Huang
    Citation: BMC Nephrology 2012 13:77
  32. Elevated serum phosphorus (P) levels have been linked to increased morbidity and mortality in dialysis patients with secondary hyperparathyroidism (SHPT) but may be difficult to control if parathyroid hormone ...

    Authors: João M Frazão, Johann Braun, Piergiorgio Messa, Bastian Dehmel, Caroline Mattin and Martin Wilkie
    Citation: BMC Nephrology 2012 13:76
  33. The interleukin (IL)18 rs360719 CC genotype is associated with the development of antibodies to hepatitis B virus surface antigen (anti-HBs) in hemodialysis (HD) patients. IL18 shares biological properties with I...

    Authors: Alicja E Grzegorzewska, Piotr M Wobszal, Adrianna Mostowska and Paweł P Jagodziński
    Citation: BMC Nephrology 2012 13:75
  34. Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease commun...

    Authors: Deidra C Crews, Raquel C Greer, Jeffrey J Fadrowski, Michael J Choi, David Doggett, Jodi B Segal, Kemi A Fawole, Pammie R Crawford and L Ebony Boulware
    Citation: BMC Nephrology 2012 13:74
  35. Fabry disease is an X-linked lysosomal storage disorder that results from a deficiency of the enzyme α-galactosidase A. Fabry disease is present in 4–5% of men with unexplained left ventricular hypertrophy or ...

    Authors: James O Burton, John P Dormer, Helen E Binns and Warren P Pickering
    Citation: BMC Nephrology 2012 13:73
  36. Central venous catheters (CVCs) are associated with early mortality in dialysis patients. However, some patients progress to end stage renal disease after an acute illness, prior to reaching an estimated glome...

    Authors: Karthik K Tennankore, Steven D Soroka and Bryce A Kiberd
    Citation: BMC Nephrology 2012 13:72
  37. Peritoneal dialysis has been proven to be a safe and effective mode of renal replacement therapy for patients with end-stage renal disease. The usage of laparoscopic catheter placement technique was increased ...

    Authors: Haiying Xie, Wei Zhang, Jun Cheng and Qiang He
    Citation: BMC Nephrology 2012 13:69
  38. This multicenter phase II study in renal transplantation compared 3 concentration-controlled ranges of FK778 (manitimus) with mycophenolate mofetil (MMF) both given in combination with tacrolimus and corticost...

    Authors: Zbigniew Wlodarczyk, Yves Vanrenterghem, Bernhard K Krämer, Jean-Paul Squifflet and Marek Ostrowski
    Citation: BMC Nephrology 2012 13:68
  39. Sexual dysfunction is common in patients with end stage renal disease (ESRD) and treatment options are limited. Observational studies suggest that nocturnal hemodialysis may improve sexual function. We compare...

    Authors: Adam Bass, Sofia B Ahmed, Scott Klarenbach, Bruce Culleton, Brenda R Hemmelgarn and Braden Manns
    Citation: BMC Nephrology 2012 13:67
  40. Medullary nephrocalcinosis and distal renal tubular acidosis are closely associated and each can lead to the other. These clinical entities are rare in patients with nephrotic syndrome and polycythaemia is an ...

    Authors: Suneth Karunarathne, Yapa Udayakumara, Dumitha Govindapala and Harshini Fernando
    Citation: BMC Nephrology 2012 13:66
  41. Anti-glomerular basement membrane glomerulonephritis and thrombotic microangiopathy are rare diseases with no known coherence.

    Authors: Thomas Idorn, Lone Schejbel, Casper Rydahl, James Goya Heaf, Karen Riis Jølvig, Marie Bergstrøm, Peter Garred and Anne-Lise Kamper
    Citation: BMC Nephrology 2012 13:64
  42. Simple renal cysts usually have benign clinical features. We report a rare case of papillary renal cell carcinoma (RCC) associated with a large recurrent simple cyst following sclerotherapy.

    Authors: Yasuhiro Hashimoto, Atsushi Imai, Noriko Tokui, Atsushi Sasaki, Hisao Saitoh, Takuya Koie and Chikara Ohyama
    Citation: BMC Nephrology 2012 13:63
  43. Living donor kidney transplantation (LDKT) is the most successful form of renal replacement therapy in terms of wait time and survival rates. However, we observed a significant inequality in the number of LDKT...

    Authors: Sohal Y Ismail, Annemarie E Luchtenburg, Willij C Zuidema, Charlotte Boonstra, Willem Weimar, Emma K Massey and Jan J Busschbach
    Citation: BMC Nephrology 2012 13:62
  44. The genetic architecture responsible for chronic kidney disease (CKD) remains incompletely described. The Oligosyndactyly (Os) mouse models focal and segmental glomerulosclerosis (FSGS), which is associated with ...

    Authors: Ashraf El-Meanawy, Jeffery R Schelling, Sudha K Iyengar, Patrick Hayden, Shrinath Barathan, Katrina Goddard, Fatima Pozuelo, Essam Elashi, Viji Nair, Matthias Kretzler and John R Sedor
    Citation: BMC Nephrology 2012 13:61
  45. Predialysis hemoglobin (Hb) may overestimate the true erithropoiesis-stimulating agents (ESA) requeriments. We tested whether predialysis Hb is a reliable predictor of the postdialysis level to better control ...

    Authors: Nieves Castillo, Patricia García-García, Antonio Rivero, Alejandro Jiménez-Sosa, Manuel Macía, María Adela Getino, María Luisa Méndez, Javier García-Pérez and Juan F Navarro-González
    Citation: BMC Nephrology 2012 13:60
  46. Chronic kidney disease(CKD) has been proposed as a risk factor for cardiovascular disease (CVD). There is conflicting evidence among community based studies regarding the association between CKD and CVD. Furth...

    Authors: Farhad Hosseinpanah, Maryam Barzin, Hosein Aghayan Golkashani, Amir A Nassiri, Farhad Sheikholeslami and Fereidoun Azizi
    Citation: BMC Nephrology 2012 13:59
  47. Estimated glomerular filtration rate (eGFR) levels have been shown to predict atherosclerotic vascular disease hospitalization and mortality. We sought to investigate the role of renal function in the predicti...

    Authors: Joshua R Lewis, Wai Lim, Satvinder S Dhaliwal, Kun Zhu, Ee Mun Lim, Peter L Thompson and Richard L Prince
    Citation: BMC Nephrology 2012 13:58

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