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  1. The main hypothesis of this study is that Oxpentifylline administration will effectively treat erythropoietin- or darbepoietin-resistant anaemia in chronic kidney disease patients.

    Authors: David Wayne Johnson, Carmel Mary Hawley, Brenda Rosser, Elaine Beller, Charles Thompson, Robert G Fassett, Paolo Ferrari, Stephen MacDonald, Eugenie Pedagogos and Alan Cass
    Citation: BMC Nephrology 2008 9:8
  2. Selenoproteins contain selenocysteine (Sec), commonly considered the 21st genetically encoded amino acid. Many selenoproteins, such as the glutathione peroxidases and thioredoxin reductases, protect cells against...

    Authors: Marsha N Blauwkamp, Jingcheng Yu, MaryLee A Schin, Kathleen A Burke, Marla J Berry, Bradley A Carlson, Frank C Brosius III and Ronald J Koenig
    Citation: BMC Nephrology 2008 9:7
  3. Concern lingers that dialysis therapy at for-profit (versus not-for-profit) hemodialysis facilities in the United States may be associated with higher mortality, even though 4 of every 5 contemporary dialysis ...

    Authors: Robert N Foley, Qiao Fan, Jiannong Liu, David T Gilbertson, Eric D Weinhandl, Shu-Cheng Chen and Allan J Collins
    Citation: BMC Nephrology 2008 9:6
  4. Administrative claims are a rich source of information for epidemiological and health services research; however, the ability to accurately capture specific diseases or complications using claims data has been...

    Authors: Alisa M Shea, Lesley H Curtis, Lynda A Szczech and Kevin A Schulman
    Citation: BMC Nephrology 2008 9:5
  5. There is evidence that dyslipidemia is associated with chronic kidney disease (CKD). Experimental studies have established that lipids are damaging to the kidney and animal intervention studies show statins at...

    Authors: Robert G Fassett, Madeleine J Ball, Iain K Robertson, Dominic P Geraghty and Jeff S Coombes
    Citation: BMC Nephrology 2008 9:4
  6. Cardiovascular events are the leading cause of death in end stage renal disease (ESRD). Adherence to phosphate binding medication plays a vital role in reducing serum phosphorus and associated cardiovascular r...

    Authors: Christina Karamanidou, Jane Clatworthy, John Weinman and Rob Horne
    Citation: BMC Nephrology 2008 9:2
  7. An ad hoc peer-review committee was jointly appointed by Drug Authorities and Industry in Germany, Austria and Switzerland in 1999/2000 to review the evidence for a causal relation between phenacetin-free anal...

    Authors: Fokke J van der Woude, Lothar AJ Heinemann, Helmut Graf, Michael Lewis, Sabine Moehner, Anita Assmann and Doerthe Kühl-Habich
    Citation: BMC Nephrology 2007 8:15
  8. The aim of this study is to evaluate the association between acute serum creatinine changes in acute renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery of renal funct...

    Authors: Jose Ramon Perez-Valdivieso, Maira Bes-Rastrollo, Pablo Monedero, Jokin de Irala and Francisco Javier Lavilla
    Citation: BMC Nephrology 2007 8:14
  9. Currently there is no effective treatment available to retard cyst growth and to prevent the progression to end-stage renal failure in patients with autosomal dominant polycystic kidney disease (ADPKD). Eviden...

    Authors: Andreas L Serra, Andreas D Kistler, Diane Poster, Marian Struker, Rudolf P Wüthrich, Dominik Weishaupt and Frank Tschirch
    Citation: BMC Nephrology 2007 8:13
  10. Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease with few treatment options other than renal replacement therapy. p21, a cyclin kinase inhibitor which has pleiotropic effects on...

    Authors: Jin-Young Park, William E Schutzer, Jessie N Lindsley, Susan P Bagby, Terry T Oyama, Sharon Anderson and Robert H Weiss
    Citation: BMC Nephrology 2007 8:12
  11. Idiopathic membranous nephropathy (IMN) is one of the most common causes of primary nephrotic syndrome in adults. However, it is a relatively rare entity in the pediatric population and there is a paucity of d...

    Authors: Ashton Chen, Rachel Frank, Suzanne Vento, Virginia Crosby, Manju Chandra, Bernard Gauthier, Elsa Valderrama and Howard Trachtman
    Citation: BMC Nephrology 2007 8:11
  12. Systemic hypertension often accompanies chronic renal failure and can accelerate its progression to end-stage renal disease (ESRD). Adjunctive moxonidine appeared to have benefits versus adjunctive nitrendipin...

    Authors: Kavi J Littlewood, Wolfgang Greiner, Dominique Baum and York Zoellner
    Citation: BMC Nephrology 2007 8:9
  13. Fibrillary glomerulonephritis is a rare cause of progressive renal dysfunction, often leading to the need for dialysis within a few years. The role of immunosuppressive treatment is still uncertain although th...

    Authors: Muhammad M Javaid, Helen Denley and Senyo Tagboto
    Citation: BMC Nephrology 2007 8:7
  14. Imatinib is a tyrosine-kinase inhibitor; for which there is limited information regarding its effects on AIDS Kaposi's sarcoma and none in patients with transplant-associated Kaposi's sarcoma. Sirolimus, an im...

    Authors: Patricia Volkow, Juan W Zinser and Ricardo Correa-Rotter
    Citation: BMC Nephrology 2007 8:6
  15. Thrombocytopenia and absent radius syndrome (TAR) is a rare genetic disorder. It is an autosomal recessive disorder characterised by radial aplasia and thrombocytopenia that may have additional anomalies. We r...

    Authors: Riaz Ahmad
    Citation: BMC Nephrology 2007 8:5
  16. It is uncertain whether patients with renal vascular disease will have renal or mortality benefit from re-establishing renal blood flow with renal revascularization procedures. The RAVE study will compare rena...

    Authors: Sheldon W Tobe, M Atri, N Perkins, R Pugash and Chaim M Bell
    Citation: BMC Nephrology 2007 8:4
  17. Mercuric chloride (HgCl2) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitia...

    Authors: María M Escribese, Elisa Conde, Ana Martín, David Sáenz-Morales, David Sancho, Guillermo Pérez de Lema, Javier Lucio-Cazaña, Francisco Sánchez-Madrid, María L García-Bermejo and Francisco M Mampaso
    Citation: BMC Nephrology 2007 8:3
  18. The prevalences and risk factors of microalbuminuria are not full described among black African diabetic patients. This study aimed at determining the prevalence of microalbuminuria among African diabetes pati...

    Authors: Janet Joy Kachuchuru Lutale, Hrafnkell Thordarson, Zulfiqarali Gulam Abbas and Kåre Vetvik
    Citation: BMC Nephrology 2007 8:2
  19. This study used a cross sectional survey to examine the effect of gender, age, and geographical location on the population prevalence of renal replacement therapy (RRT) provision in Wales.

    Authors: Hugo C van Woerden, Jane Wilkinson, Martin Heaven and Jason Merrifield
    Citation: BMC Nephrology 2007 8:1
  20. Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually d...

    Authors: Aman Sharma, Ajay Wanchu, V Mahesha, V Sakhuja, Pradeep Bambery and Surjit Singh
    Citation: BMC Nephrology 2006 7:18
  21. Small vessel vasculitides are known to follow a devastating course towards end-stage renal disease, unless treated with immunosuppressive regiments. We investigated the value of clinical, histological and immu...

    Authors: Efstathios Alexopoulos, Lazaros Gionanlis, Ekaterini Papayianni, Elizabeth Kokolina, Maria Leontsini and Dimitrios Memmos
    Citation: BMC Nephrology 2006 7:16
  22. The Renin-Angiotensin system (RAS) is a key regulator of both blood pressure and kidney functions and their interaction. In such a situation, genetic variability in the genes of different components of RAS is ...

    Authors: Gaurav Tripathi, Poonam Dharmani, Faisal Khan, RK Sharma, Vinod Pandirikkal Baburajan and Suraksha Agrawal
    Citation: BMC Nephrology 2006 7:15
  23. Previous studies have shown that in male rats, exposure to maternal protein restriction either in utero or whilst suckling can have profound effects on both longevity and kidney telomere lengths. This study monit...

    Authors: Clive J Petry, Bridget J Jennings, Lynwen A James, Charles N Hales and Susan E Ozanne
    Citation: BMC Nephrology 2006 7:14
  24. Due to its strong intra- and inter-individual variability, predicting the ideal erythropoietin dose is a difficult task. The aim of this study was to re-evaluate the impact of the main parameters known to infl...

    Authors: Luca Gabutti, Nathalie Lötscher, Josephine Bianda, Claudio Marone, Giorgio Mombelli and Michel Burnier
    Citation: BMC Nephrology 2006 7:13
  25. Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manife...

    Authors: Plamen S Dimitrov, Valeri A Simeonov, Svetlana D Tsolova, Angel G Bonev, Rossitza B Georgieva and Wilfried J Karmaus
    Citation: BMC Nephrology 2006 7:12
  26. Medicare beneficiaries without prescription drug coverage consistently fill fewer prescriptions than beneficiaries with some form of drug coverage due to cost. ESRD patients, who are disproportionately poor an...

    Authors: Anisa I Nayeem and Glenn M Chertow
    Citation: BMC Nephrology 2006 7:11
  27. Advancements in immunosuppressive therapy have significantly improved patient and graft survival following renal transplantation. This is paralleled by an increasing occurrence of posttransplantation malignancy.

    Authors: Roland Schmitt, Ute Kettritz, Friedrich C Luft and Ralph Kettritz
    Citation: BMC Nephrology 2006 7:9
  28. Many patients with end-stage renal disease use a central venous catheter for hemodialysis access. A large majority of these catheters malfunction within one year of insertion, with up to two-thirds due to thro...

    Authors: Brenda R Hemmelgarn, Louise Moist, Rachel M Pilkey, Charmaine Lok, Marc Dorval, Paul YW Tam, Murray J Berall, Martine LeBlanc, Edwin B Toffelmire, Braden J Manns and Nairne Scott-Douglas
    Citation: BMC Nephrology 2006 7:8
  29. A reduction in the number of podocytes and podocyte density has been documented in the kidneys of patients with diabetes mellitus. Additional studies have shown that podocyte injury and loss occurs in both dia...

    Authors: Brian Siu, Jharna Saha, William E Smoyer, Kelli A Sullivan and Frank C Brosius III
    Citation: BMC Nephrology 2006 7:6
  30. Chelation therapy with sodium edetate (EDTA) improved renal function and slowed the progression of renal insufficiency in patients subjected to lead intoxication. This study was performed to identify the under...

    Authors: Chiara Foglieni, Alessandro Fulgenzi, Paolo Ticozzi, Fabio Pellegatta, Clara Sciorati, Daniela Belloni, Elisabetta Ferrero and Maria Elena Ferrero
    Citation: BMC Nephrology 2006 7:5
  31. Chronic kidney disease (CKD) has been linked to higher heart failure (HF) risk. Anemia is a common consequence of CKD, and recent evidence suggests that anemia is a risk factor for HF. The purpose of this stud...

    Authors: Jean-Christophe Luthi, W Dana Flanders, Michel Burnier, Bernard Burnand and William M McClellan
    Citation: BMC Nephrology 2006 7:3
  32. Nocturnal hemodialysis (NHD) is an alternative to conventional three times per week hemodialysis (CvHD) and has been reported to improve several health outcomes. To date, no randomized controlled trial (RCT) h...

    Authors: Michael Walsh, Braden J Manns, Scott Klarenbach, Robert Quinn, Marcello Tonelli and Bruce F Culleton
    Citation: BMC Nephrology 2006 7:2
  33. Lim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme. Conditional ablat...

    Authors: You-Tzung Chen, Akio Kobayashi, Kin Ming Kwan, Randy L Johnson and Richard R Behringer
    Citation: BMC Nephrology 2006 7:1
  34. Despite multiple causes, Chronic Kidney Disease is commonly associated with proteinuria. A previous study on Non Obese Diabetic mice (NOD), which spontaneously develop type 1 diabetes, described histological a...

    Authors: Karen HS Wilson, Richard A McIndoe, Sarah Eckenrode, Laurence Morel, Anupam Agarwal, Byron P Croker and Jin-Xiong She
    Citation: BMC Nephrology 2005 6:17
  35. Crescentic nephritis is characterized by formation of cellular crescents that soon become fibrotic and result in irreversible damage, unless an effective immunosuppressive therapy is rapidly commenced. TGF-β1 is ...

    Authors: Dimitrios S Goumenos, Pantelitsa Kalliakmani, Sotiris Tsakas, Florentia Sotsiou and John G Vlachojannis
    Citation: BMC Nephrology 2005 6:16
  36. IgA nephropathy (IgAN) or Berger's disease, is the most common glomerulonephritis in the world diagnosed in renal biopsied patients. The involvement of genetic factors in the pathogenesis of the IgAN is eviden...

    Authors: Francesco P Schena, Giuseppina Cerullo, Diletta D Torres, Francesco Scolari, Marina Foramitti, Antonio Amoroso, Doroti Pirulli, Jürgen Floege, Peter R Mertens, Klaus Zerres, Efstathios Alexopoulos, Dimitrios Kirmizis, Leopoldo Zelante, Luigi Bisceglia, Gian M Ghiggeri and Giovanni M Frascà
    Citation: BMC Nephrology 2005 6:14
  37. It has been established that hypothyroidism protects rats against renal ischemia and reperfusion (IR) oxidative damage. However, it is not clear if hypothyroidism is able to prevent protein tyrosine nitration,...

    Authors: Verónica M Tenorio-Velázquez, Diana Barrera, Martha Franco, Edilia Tapia, Rogelio Hernández-Pando, Omar Noel Medina-Campos and José Pedraza-Chaverri
    Citation: BMC Nephrology 2005 6:12
  38. The National Kidney Foundation has formulated clinical practice guidelines for patients with chronic kidney disease (K/DOQI). However, little is know about how many patients actually achieve these goals in a d...

    Authors: Oliver Lenz, Durga P Mekala, Daniel V Patel, Alessia Fornoni, David Metz and David Roth
    Citation: BMC Nephrology 2005 6:11
  39. The association between intake of non-phenacetin-containing analgesics and the occurrence of chronic renal failure is still controversially discussed. A new epidemiologic study was planned and conducted in Ger...

    Authors: Lothar AJ Heinemann, Edeltraut Garbe, Michael Lewis, Fokko van der Woude and Helmut Graf
    Citation: BMC Nephrology 2005 6:9

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